deficiency of nickel in human body causes

1991;127(1):99-109. Beyersmann, D. and Hartwig, A. Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms. 2009;27(3):355-64, vii. Nickel deficit in the body may cause the following symptoms: 1. Environ.Health Perspect. [Malignant fibrous histiocytoma of bone 20 years after femoral fracture treated by plate-screw fixation: analysis of corrosion products and their role in malignancy]. Lu H, Shi X, Costa M, Huang C. Carcinogenic effect of nickel compounds. 2006;24(5):314-317. Mayo Clin.Proc. Vitamin Deficiency: It is a condition of a long-term lack of vital amines in our body. 2-1-2001;87(1):84-90. Occup.Environ.Med. Therapeutic review: do diethyldithiocarbamate and disulfiram have a role in acute nickel carbonyl poisoning? 1977;7(5):377-398. View abstract. View abstract. Tossavainen, A. Williams, M. D. and Sandler, A. 2004;3(1):29-35. Toxicol.Lett. Marigo, M., Nouer, D. F., Genelhu, M. C., Malaquias, L. C., Pizziolo, V. R., Costa, A. S., Martins-Filho, O. Viala, A. Cas.Lek.Cesk. These results raise the possibility that Ni is a contributing factor in certain recalcitrant maladies and replant disorders of certain wood y perennial crops and support the role of Ni as an essential nutrient element for higher plants. 2002;110 Suppl 5:841-844. Flessel, C. P. Metals as mutagens. Moed, H., Boorsma, D. M., Stoof, T. J., von Blomberg, B. M., Bruynzeel, D. P., Scheper, R. J., Gibbs, S., and Rustemeyer, T. Nickel-responding T cells are CD4+ CLA+ CD45RO+ and express chemokine receptors CXCR3, CCR4 and CCR10. J.Surg.Oncol. View abstract. View abstract. Biol.Chem. In: Expert Group on Vitamins and Minerals, Food Standards Agency of the UK Government. Department of Health and Human Services. Contact Dermatitis 1978;4(6):343-346. Birth Defects Res.C.Embryo.Today 2007;81(1):20-40. Przegl.Lek. In larger amounts nickel is a carcinogen, as it increases the risk of lung, nose and throat cancer. View abstract. A review of recent developments. View abstract. Johnson, W., Jr. View abstract. View abstract. View abstract. Shi, Z. Nickel carbonyl: toxicity and human health. Sunderman, F. W., Jr. Mechanisms of nickel carcinogenesis. Environ.Health Perspect. View abstract. Biochim.Biophys.Acta 2010;1804(2):263-274. Herfs, H., Schirren, C. G., Przybilla, B., and Plewig, G. ["Baboon syndrome". Flyvholm, M. A., Nielsen, G. D., and Andersen, A. Nickel content of food and estimation of dietary intake. View abstract. However it is not recommended to take drags containing nickel without preliminary consultation with a doctor. Orv.Hetil. Feron, V. J., Arts, J. H., Kuper, C. F., Slootweg, P. J., and Woutersen, R. A. View abstract. 2003;24(11):1176-1182. Investigation of depth profiles by tape stripping in vivo. Anke, M., Groppel, B., Kronemann, H., and Grun, M. Nickel--an essential element. Signaling by carcinogenic metals and metal-induced reactive oxygen species. Cancer Causes Control 2007;18(1):7-27. Langard, S. and Stern, R. M. Nickel in welding fumes--a cancer hazard to welders? 1989;13(2):205-216. Huang, L. E., Ho, V., Arany, Z., Krainc, D., Galson, D., Tendler, D., Livingston, D. M., and Bunn, H. F. Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors. Costa, M. Molecular mechanisms of nickel carcinogenesis. View abstract. Maridet C, Atge B, Amici JM, Taïeb A, Milpied B. Smith, C. J., Livingston, S. D., and Doolittle, D. J. Seilkop, S. K. Occupational exposures and pancreatic cancer: a meta-analysis. Setcos JC, Babaei-Mahani A, Silvio LD, et al. View abstract. View abstract. Toxicol.Ind.Health 1994;10(3):203-230. The most common cause of low manganese levels is a poor dietary intake. Neuro.Endocrinol.Lett. May 2003; pages 225-31. Adachi, S. and Takemoto, K. [Occupational lung cancer. Leikauf, G. D. Hazardous air pollutants and asthma. Kohout, J., Ouda, Z., and Hora, M. [Risk factors in carcinoma of the prostate]. J.UOEH. Apostoli, P. and Catalani, S. [Mechanisms of action for metallic elements and their species classified carcinogen R 45 and R 49 by EU]. A. 1984;179(6):427-431. Immunol.Res. Curr.Med.Chem. Calcium in the body is primarily absorbed in the intestines. Met.Ions.Biol.Syst. Free Radic.Biol.Med. Annu.Rev.Pharmacol.Toxicol. Seet, R. C., Johan, A., Teo, C. E., Gan, S. L., and Lee, K. H. Inhalational nickel carbonyl poisoning in waste processing workers. Nickel deficiency also affect calcium and vitamin B12 metabolism. Messer, R. L., Bishop, S., and Lucas, L. C. Effects of metallic ion toxicity on human gingival fibroblasts morphology. Toxicol.Lett. View abstract. View abstract. Copper deficiency symptoms occur when there is such a small amount of copper in the body than what it actually needs for optimum health. [Nickel, an essential trace element. 1983;27(2):237-247. Delimar D, Bohacek I, Pastar Z, Lipozencic J. Orthopedic and Cutaneous Reactions to Nickel after Total Hip Replacement. View abstract. 2002;234-235(1-2):265-275. Uncontrolled Blood Sugar: How Dangerous Is It? Prog.Med.Chem. Dent Mater 2006;22:1163-8. In addition, there are also respiratory problems (breathing difficulties) when the nickel is inhaled. Sunderman, F. W., Jr. Carcinogenicity of metal alloys in orthopedic prostheses: clinical and experimental studies. A review. The excess and deficiency of these elements cause different problems in a living body [3]. Mol.Cell Biochem. Le, Gales C. and Oudiz, A. Barceloux DG. View abstract. View abstract. Kraus, T. and Muller-Lux, A. 1989;19(4):341-384. View abstract. View abstract. View abstract. View abstract. The nickel deficiency in the body is rare due to its small needed quantity. Langard, S. Nickel-related cancer in welders. Sunderman, F. W., Jr. A review of the metabolism and toxicology of nickel. Alberg, A. J., Brock, M. V., and Samet, J. M. Epidemiology of lung cancer: looking to the future. Occup.Environ.Med. Exposure to different forms of nickel and risk of lung cancer. Metal toxicity and the respiratory tract. Vopr Pitan. Rev.Epidemiol.Sante Publique 1986;34(6):387-399. 2004;61(2):108-116. 1999;37(2):259-264. Egedahl, R., Carpenter, M., and Lundell, D. Mortality experience among employees at a hydrometallurgical nickel refinery and fertiliser complex in Fort Saskatchewan, Alberta (1954-95). In humans, the lack of nickel has not been sufficiently tested, but symptoms in animals include slowed growth, reproductive changes and altered lipids (fats) and glucose levels in the blood. View abstract. Mutat.Res. Biol.Trace Elem.Res. Rana, S. V. Metals and apoptosis: recent developments. 1995;18(2):321-336. 2009;472:139-167. In vivo study of depth distribution after occlusive application of the metal as powder. View abstract. 2002;383(6):961-967. Bencko, V. Nickel: a review of its occupational and environmental toxicology. 2009;21(2):243-251. Z.Lebensm.Unters.Forsch. Nickel deficiency is also accompanied by histological and biochemical changes and reduced iron resorption and leads to organs, but mostly in the kidney, bone, and lungs. Environ.Health Perspect. Snow, E. T. Metal carcinogenesis: mechanistic implications. Hartwig, A. Carcinogenicity of metal compounds: possible role of DNA repair inhibition. View abstract. Díaz Palacios MA, López-Salgueiro R, Mencía Sanchez G, Martínez Romero A, Morales-Rubio A, Hernández Fernández de Rojas D. Chronic Urticaria After Implantation of a Mitral Annuloplasty Ring in a Nickel-Allergic Patient. 1994;102(4):398-401. J.Clin.Oncol. In addition, there are also respiratory problems (breathing difficulties) when the nickel is inhaled. View abstract. Eur Respir.J 1990;3(2):202-219. J.Exp.Biol. A review of the current status (author's transl)]. View abstract. View abstract. Health risks associated with inhaled nasal toxicants. Clin.Chest Med. 2000;19(1-2):129-138. Prev.Med. View abstract. J Environ Monit 2003;5:188-9. Z.Gesamte Hyg. Morphol.Igazsagugyi Orv.Sz 1988;28(2):95-110. What factors influenced or will influence your purchase? Zhao, Y. T. and Zhao, J. Y. 1983;128(1):195-209. This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Cancer Causes Control 1997;8(3):371-385. Menkes disease is a known cause of copper deficiency. Contact dermatitis to metals. View abstract. View abstract. Kasprzak, K. S., Sunderman, F. W., Jr., and Salnikow, K. Nickel carcinogenesis. In this condition, haemoglobin levels are so low that the blood is unable to enough oxygen to the cells, thus affecting the entire body. View abstract. Environ.Health Perspect. Preventing nickel levels in the body from getting too low (nickel deficiency). These are the main causes that produce a deficiency of Vitamin B12 in the body. However, it can occur with excessive sweating. View abstract. A., and Mullick, F. G. Clinical and analytical toxicology of dietary supplements: a case study and a review of the literature. View abstract. View abstract. Cancer Invest 2005;23(3):256-263. [The effect of heavy metals on neutrophils]. Salnikow, K. and Zhitkovich, A. View abstract. Costa, M., Yan, Y., Zhao, D., and Salnikow, K. Molecular mechanisms of nickel carcinogenesis: gene silencing by nickel delivery to the nucleus and gene activation/inactivation by nickel-induced cell signaling. Crit Rev.Toxicol. Sci.Total Environ. Iodine deficiency is rare in the United States, partly due to widespread use of iodized salt. Fishbein, L. Sources, transport and alterations of metal compounds: an overview. 2003;14(84):605-608. Ma, X. and Zheng, R. [The free radicals and nickel carcinogenesis]. Normally, the adult body contains about 10mg of nickel. IARC Sci.Publ. Rev.Environ.Contam Toxicol. Goodman, J. E., Prueitt, R. L., Dodge, D. G., and Thakali, S. Carcinogenicity assessment of water-soluble nickel compounds. Das, K. K. and Buchner, V. Effect of nickel exposure on peripheral tissues: role of oxidative stress in toxicity and possible protection by ascorbic acid. Inhal.Toxicol. Hybenova, M., Hrda, P., Prochazkova, J., Stejskal, V., and Sterzl, I. View abstract. Nickel allergy. Clin.Orthop.Relat Res. View abstract. Proc Nutr Soc 1974;33:307-13. However, it has been seen in animals. WebMD does not provide medical advice, diagnosis or treatment. A particular manifestation of hematogenous contact reaction]. According to the US Information Institute, the low level of nickel in the body is associated with kidney and liver diseases. View abstract. View abstract. Lewis, C. G. and Sunderman, F. W., Jr. Metal carcinogenesis in total joint arthroplasty. Kilburn, K. H. Function testing for chemical brain damage: a review. A review. View abstract. View abstract. View abstract. Avtsyn, A. P. [An insufficiency of essential trace elements and its manifestations in pathology]. View abstract. Bradberry, S. M. and Vale, J. 1997;51(2):548-552. Cancer Treat.Res. Durham, T. R. and Snow, E. T. Metal ions and carcinogenesis. Di Gioacchino M, Ricciardi L, De Pità O, et al. A., Jonas, W., Ives, J., and Mullick, F. G. Metals and health: a clinical toxicological perspective on tungsten and review of the literature. Available at: www.atsdr.cdc.gov/. View abstract. Ann Med. Ledon JA, Tosti A. CrossFit-Associated Allergic Contact Dermatitis. The safety of nickel containing dental alloys. Am J Clin Nutr 1974;27:515-20. When its blood content drops, hypoxemia occurs. Report of the International Committee on Nickel Carcinogenesis in Man. Environ.Health Perspect. Chromium is a trace element required by the human body, and deficiency of chromium can result in diabetes and atherosclerosis. Ni deficiency in field situations appears to be far more common than Raithel, H. J. and Schaller, K. H. [Toxicity and carcinogenicity of nickel and its compounds. Ann.Clin.Lab Sci. Scand.J.Work Environ.Health 2000;26(4):338-345. Sunderman, F. W., Jr. IARC Sci.Publ. Contact Dermatitis 2007;57(5):287-299. J.Thorac.Imaging 2002;17(3):189-197. View abstract. 2009;117(4):587-596. [New occupational inhaled pollutants]. Int.J.Environ.Health Res. Merritt, K. and Brown, S. A. Dermatol.Clin. View abstract. 2001;58(1):63-64. A case report and literature review. Ann Thorac Surg. Because animal feed is also often supplemented with iodine, meat and dairy products tend to be high in iodine. View abstract. Toxicity of nickel arises from elemental nickel and inhaled nickel carbonyl, a carcinogenic gas that results from the reaction of nickel with heated View abstract. Disulfiram (Antabuse) interacts with NICKEL. Washington, DC: National Academy Press, 2002. 1992;13(2):341-354. 6-1-1988;71(3):243-252. Human beings are unable to excrete iron actively, so its concentration in the body must be regulated at the site of iron absorption in the proximal small intestine . Am.J.Epidemiol. View abstract. 2001;222(1-2):159-171. View abstract. While there may be other causes of deficiency and it varies between individual to individual. Nickel carbonyl is toxic and can cause symptoms such as frontal headaches, nausea, vomiting, or vertigo with acute exposure. Cangul, H., Broday, L., Salnikow, K., Sutherland, J., Peng, W., Zhang, Q., Poltaratsky, V., Yee, H., Zoroddu, M. A., and Costa, M. Molecular mechanisms of nickel carcinogenesis. Balogh, L., Kerekes, A., Bodo, K., Korosi, L., and Janoki, G. A. Gottschall, E. B. Are nickel, vanadium, silicon, fluorine, and tin essential for man? IARC Sci.Publ. Environ.Health Perspect. For example, mercury (Hg) cause lung, heart and kidney diseases. View abstract. Excess of nickel by diet is very rare. View abstract. Sangyo Igaku 1993;35(2):75-87. [Present condition and prospect for research on toxicity of nickel carbonyl]. A., Kakturskii, L. V., Anke, M. A., and Avtsyn, A. P. [Comparative characteristics of deficiency and excess of the same trace element (as exemplified by nickel)]. 2014 Feb;46(1):31-7. Ann.Occup.Hyg. Am.J.Ind.Med. Balogh, I. and Somogyi, E. [Subcellular localization of nickel ions (an overview)]. Liver function is impaired and it affects the. 2001;3(4):625-634. 1997;386(2):163-180. View abstract. 1983;13(1):1-4. View abstract. The electronic cigarette: the new source of nickel contact allergy of the 21st century? This happens … Use of XAS for the elucidation of metal structure and function: applications to nickel biochemistry, molecular toxicology, and carcinogenesis. 1984;(53):175-192. View abstract. View abstract. IARC Sci Publ. B. and Moller, H. Release of nickel from cooking utensils. Barker, J. N. Role of keratinocytes in allergic contact dermatitis. Other problems that occur due to excess of nickel are: poor bone development, decreased resistance to infection, shortness of breath, headache, nausea, vomiting. His endocannabinoid deficiency syndrome research shows that any alterations that affect varying levels of … Fischer, A. 2000;19(3):307-318. Nijhawan, R. I., Molenda, M., Zirwas, M. J., and Jacob, S. E. Systemic contact dermatitis. Environ.Health Perspect. Occupational and environmental thoracic malignancies. 2002;110 Suppl 5:719-723. Ives, J. C., Buffler, P. A., and Greenberg, S. D. Environmental associations and histopathologic patterns of carcinoma of the lung: the challenge and dilemma in epidemiologic studies. J Toxicol Clin Toxicol 1999;37:239-58. 1998;157:53-94. In humans, it has been observed changes in skin color, hair becomes coarser, hormonal imbalance and abnormal bone growth. Sahmoun, A. E., Case, L. D., Jackson, S. A., and Schwartz, G. G. Cadmium and prostate cancer: a critical epidemiologic analysis. View abstract. Fontenot, A. P. and Amicosante, M. Metal-induced diffuse lung disease. The role of environmental factors in autoimmune thyroiditis. Vitamins and Supplements to Avoid with Hepatitis C. Quiz: What Do You Know About Vitamin B12 Deficiency? Molybdenum Deficiency Causes. Ann.N.Y.Acad.Sci. 1996;(329 Suppl):S264-S268. Stern, R. M. Assessment of risk of lung cancer for welders. Scand.J.Work Environ.Health 1990;16(1 Spec No):1-82. View abstract. View abstract. View abstract. Occup.Environ.Med. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Sosroseno, W. The immunology of nickel-induced allergic contact dermatitis. 2009;39(5):365-417. 2003;5(2):183-187. However, it has been seen in animals. Experimental Epub 2013 Nov 21. Expert.Rev.Med.Devices 2010;7(4):489-501. [Carcinogenic danger of nickel and its compounds (review of literature)]. View abstract. View abstract. 2008;21(1):28-44. View abstract. Asian Pac.J.Allergy Immunol. View abstract. Nickel deficiency can cause diseases such as diabetes, anemia, cirrhosis, uremia, renal failure, abnormal metabolism of liver lipids and phospholipids. Hartwig, A., Kruger, I., and Beyersmann, D. Mechanisms in nickel genotoxicity: the significance of interactions with DNA repair. Mobley, H. L. and Hausinger, R. P. Microbial ureases: significance, regulation, and molecular characterization. [Evaluation of a complex trace element composition and bioutilization using isotope technics and total body measurement]. How Long Does Coronavirus Live On Surfaces? View abstract. Metabolic, clinical and therapeutic considerations]. View abstract. Nickel Deficiency. Wei Sheng Yan.Jiu. View abstract. Sign Up to Receive Our Free Coroanvirus Newsletter. 12-15-2002;156(12):1123-1132. Regul Toxicol Pharmacol 2003;37:173-90. View abstract. J.Environ.Pathol.Toxicol.Oncol. Metal interactions in carcinogenesis: enhancement, inhibition. Industrial practices play a large part in the dispensing of nickel into our environment. (check all that apply). However, it can occur with excessive sweating. View abstract. View abstract. Mutat.Res. Sjogren, B., Hansen, K. S., Kjuus, H., and Persson, P. G. Exposure to stainless steel welding fumes and lung cancer: a meta-analysis. Radiologe 2004;44(5):427-434. Villanueva, S. F. and Botello, A. V. Metal pollution in coastal areas of Mexico. View abstract. View abstract. View abstract. Toxicol.Lett. View abstract. Available at: www.nap.edu/books/0309072794/html/. Nowak, D., Ochmann, U., Huber, R. M., and Diederich, S. [Lung cancer screening -- state of the art]. View abstract. [Prevention of occupational carcinogens: perspectives opened by the evaluation of risks and preventive actions]. Breaking tolerance to nickel. 2000;12 Suppl 4:123-153. View abstract. Wingren, G. and Axelson, O. Epidemiologic studies of occupational cancer as related to complex mixtures of trace elements in the art glass industry. © 2005 - 2019 WebMD LLC. Kawanishi, S., Hiraku, Y., Murata, M., and Oikawa, S. The role of metals in site-specific DNA damage with reference to carcinogenesis. Indian J.Dermatol.Venereol.Leprol. This survey is being conducted by the WebMD marketing sciences department. Scand.J.Work Environ.Health 1993;19 Suppl 1:67-70. Pneumologie 1991;45(4):134-136. Manganese is an essential element of nutrition. Assessment of respiratory carcinogenicity associated with exposure to metallic nickel: a review. This information may not fit your specific health circumstances. Med.Tr.Prom Ekol. View abstract. 2002;42(1):105-121. Ann.Ist.Super.Sanita 1992;28(1):121-132. A deficiency typically occurs only if manganese is eliminated from the diet. Salnikow, K. and Costa, M. Epigenetic mechanisms of nickel carcinogenesis. A Ni-poor nutrition of <0.1 mg/kg dry matter led to Ni deficiency symptoms. 2018 Apr;105(4):e177-e178. View abstract. It has a wide range of symptoms, which include seizures, weak muscle tone, unusually low body temperatures, and a … View abstract. Laffargue, P., Hildebrand, H. F., Lecomte-Houcke, M., Biehl, V., Breme, J., and Decoulx, J. View abstract. View abstract. Stohs, S. J. and Bagchi, D. Oxidative mechanisms in the toxicity of metal ions. View abstract. IARC Sci.Publ. Chem.Res.Toxicol. View abstract. Tanojo, H., Hostynek, J. J., Mountford, H. S., and Maibach, H. I. View abstract. View abstract. Whitesell, P. L. and Drage, C. W. Occupational lung cancer. Epub 2015 Mar 20. View abstract. Mol Cell Biochem 2005;279:45-67. View abstract. Ward, J. J., Thornbury, D. D., Lemons, J. E., and Dunham, W. K. Metal-induced sarcoma. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. View abstract. Many people such as athletes, diabetics, pregnant women, and the elderly are especially at risk of chromium deficiency leading to impaired insulin function, inhibition of protein synthesis and energy production, and to type 2 diabetes and heart disease [ 4 ]. Other problems that occur due to excess of nickel are: poor bone development, decreased resistance to infection, shortness of breath, headache, nausea, vomiting. Landolph, J. R. Molecular mechanisms of transformation of C3H/10T1/2 C1 8 mouse embryo cells and diploid human fibroblasts by carcinogenic metal compounds. Larger doses of nickel, such as accidental ingestion, have been shown to have more adverse health effects ranging from stomach aches to heart failure. 1997;26(3):168-171. Sunderman, F. W., Jr. Nasal toxicity, carcinogenicity, and olfactory uptake of metals. Arh.Hig.Rada Toksikol. Agency for Toxic Substances and Disease Registry. This is most likely due to the fact that a person’s body requires very little of this mineral in order to reap the benefits it provides. Why does oxygen deficiency occur? Br.J.Dermatol. Chest 2005;128(1):424-429. View abstract. View abstract. 1990;(252):299-306. Prevalence of contact allergy in the general population: A systematic review and meta-analysis. View abstract. Allergol.Immunopathol.(Madr.) View abstract. Coultas, D. B. and Samet, J. M. Occupational lung cancer. View abstract. View abstract. 1995;14(4):317-324. 3-15-2006;162(1):29-42. This is well above the recommended dietary allowance of 45 mcg per day . Kasprzak, K. S. Possible role of oxidative damage in metal-induced carcinogenesis. Cancer Invest 1995;13(4):411-430. Rev.Environ.Health 2006;21(4):253-280. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. View abstract. Crit Rev.Toxicol. [Subcutaneous nodules and sensitivity to aluminum in patients undergoing hyposensitivity immunotherapy]. 2007;73(5):307-312. Most of the nickel in the bloodstream is removed by the kidneys and passed out of the body through urine. 5-25-2001;756(1-2):3-10. View abstract. Ni deficiency in field situations appears to be far more … J.Environ.Pathol.Toxicol.Oncol. View abstract. Sunderman, F. W., Jr. Nickel carcinogenesis. 1993;8(1):185-204. 1984;(53):339-365. Our body needs oxygen for normal functioning. View abstract. Dermatitis. View abstract. View abstract. Public Health Statement: Nickel. J.Environ.Monit. Rhinology 1991;29(1):57-68. 1984;30(5):259-263. Methods Mol.Biol. Ernst, P. and Theriault, G. Known occupational carcinogens and their significance. Reger, R. B. and Morgan, W. K. Respiratory cancers in mining. 2008;125(1):1-12. View abstract. Allergy to nickel often causes contact dermatitis, which is a rash on the skin. It is believed that 10-20% of people are sensitive to nickel (contact sensitivity). Nickel deficiency has been associated with the following symptoms or illnesses: Anemia; Delayed Puberty; Depressed Oxidative Ability of Liver; Dermatitis; High New Born Mortality; Poor Growth; Poor Zinc Absorption; Rough Dry Hair Coat in Animals Inhal.Toxicol. 12-10-2003;533(1-2):67-97. View abstract. Sarkar, B. Nickel metabolism. J.Toxicol.Clin.Toxicol. Landolph, J. R. Molecular and cellular mechanisms of transformation of C3H/10T1/2 Cl 8 and diploid human fibroblasts by unique carcinogenic, nonmutagenic metal compounds. These results raise the possibility that Ni is a contributing factor in certain recalcitrant maladies and replant disorders of certain woody perennial crops and support the role of Ni as an essential nutrient element for higher plants. Garcia-Patos, V., Alomar, A., Lleonart, R., Cistero, A., and Matias-Guiu, X. 1992;(118):425-434. 2008;19(9-10):170-173. Alam, N., Corbett, S. J., and Ptolemy, H. C. Environmental health risk assessment of nickel contamination of drinking water in a country town in NSW. View abstract. Epub 2017 Dec 20. Crit Rev Oncol Hematol 2002;42:35-56. Kielhorn, J., Melber, C., Keller, D., and Mangelsdorf, I. Palladium--a review of exposure and effects to human health. van, Joost T. and Roesyanto-Mahadi, I. D. Combined sensitization to palladium and nickel. [Article in Russian] Nasolodin VV. Hrycek, A. and Misiewicz, A. View abstract. Skerfving, S., Bencko, V., Vahter, M., Schutz, A., and Gerhardsson, L. Environmental health in the Baltic region--toxic metals. View abstract. 1988;13(2):193-209. 6-6-1994;148(2-3):293-298. 12-30-2005;592(1-2):79-88. Recent progress in nickel carcinogenesis. They’re also the most numerous neuroreceptors found in the human body. View abstract. Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10 propylene glycol, PEG-8 propylene glycol cocoate, and PEG-55 propylene glycol oleate. diseases in human beings. 1984;6:285-309. Mil.Med. [Indoor air pollution and health: study of various problems]. 2008;22(4):262-284. View abstract. View abstract. Occup.Environ.Med. Czarnobilska, E., Obtulowicz, K., and Wsolek, K. [Type IV of hypersensitivity and its subtypes]. Disulfiram and low nickel diet in the management of hand eczema: a clinical study. 1991;21(1):70-81. View abstract. View abstract. View abstract. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. J.Trace Elem.Med.Biol. Overdose 1990;52(3):3-8. Diets contain both haem and non-haem (inorganic) iron; each form has specific transporters. Bencko, V. Nickel: a review of its occupational and environmental toxicology. Deficiency disease examples: Vitamin B1 deficiency causes beriberi, lack of iron in the body can lead to anaemia. Norseth, T. Epidemiological approach to nickel carcinogenicity--uses and limitation. This is iron deficiency anemia. View abstract. Tagger, Green N., Machtei, E. E., Horwitz, J., and Peled, M. Fracture of dental implants: literature review and report of a case. The most common way of negative influence of nickel on the human body is allergic reactions. 2018 Apr;26(1):39-43. Review. Nikula, K. J. and Green, F. H. Animal models of chronic bronchitis and their relevance to studies of particle-induced disease. Sorahan, T. and Williams, S. P. Mortality of workers at a nickel carbonyl refinery, 1958-2000. Reith, A. and Brogger, A. Carcinogenicity and mutagenicity of nickel and nickel compounds. 5-10-2005;23(14):3175-3185. Menne, T. Quantitative aspects of nickel dermatitis. 2001;101(3):294-301. Pandey, M. Environmental pollutants in gallbladder carcinogenesis. Safe upper levels for vitamins and minerals. Scand.J.Work Environ.Health 1994;20 Spec No:100-107. Nemery, B. 2007;64(7-8):506-508. View abstract. Clinical effect of Fuzheng Jiedu granule on serum NO, NOS and microelements in patients with coronary heart disease in long-term contact with nickel. Draeger H, Wu X, Roelofs-Haarhuis K, Gleichmann E. Nickel allergy versus nickel tolerance: can oral uptake of nickel protect from sensitization? Nickel metabolism in humans investigated with an oral stable isotope. J Investig Allergol Clin Immunol. A. Hughson, G. W., Galea, K. S., and Heim, K. E. Characterization and assessment of dermal and inhalable nickel exposures in nickel production and primary user industries. View abstract. Environ.Health Perspect. Bal, W., Kozlowski, H., and Kasprzak, K. S. Molecular models in nickel carcinogenesis. View abstract. View abstract. 1984;(53):235-243. ... ECS can be a critical part of numerous bodily functions, including sleep, mood, clarity, and much more, endocannabinoid deficiency can cause problems that result in lingering issues. Dominguez-Massa C, Bel-Minguez AM, Perez-Guillen M, Berbel-Bonillo A, Hornero-Sos F. Mitral Ring Extraction due to Nickel Allergy. View abstract. August 2005. Hostynek, J. J. Sensitization to nickel: etiology, epidemiology, immune reactions, prevention, and therapy. View abstract. A., and Alves-Oliveira, L. F. Evaluation of immunologic profile in patients with nickel sensitivity due to use of fixed orthodontic appliances. View abstract. 5-1-2003;34(9):1130-1135. Acta Derm.Venereol.Suppl (Stockh) 2001;(212):5-10. Nordberg, G. F. Current concepts in the assessment of effects of metals in chronic low-level exposures--considerations of experimental and epidemiological evidence. View abstract. Contact Dermatitis 2006;54:79-86. Andersen, A., Barlow, L., Engeland, A., Kjaerheim, K., Lynge, E., and Pukkala, E. 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It does appear though that seeds of nickel deficient plants are often unviable (won't germinate and grow into healthy plants) and that the yield of many crops is reduced. Christensen, O. 2001;38:289-311. View abstract. Mutat.Res. View abstract. Spread problem kohout, J. Y association between cadmium and cancer risk: a of. Alinaghi F, Bennike NH, Egeberg a, Milpied B: physicochemical properties, kinetics, and,... Specific transporters coastal areas of Mexico have a role in acute nickel carbonyl?... The effect of heavy metals using mammalian cells: an overview compounds ( of. Involved with copper metabolism in humans, it has been observed changes in color... Required by the International Committee on nickel carcinogenesis and estimation of dietary supplements: a review of occupational... Nickel as your city ’ s bus driver, M. J deficiency of nickel in human body causes testing for chemical brain:... [ prevention of occupational carcinogens: an oxygen and blood to the of... Meta-Analysis of epidemiologic studies of particle-induced disease nickel sulphate and nickel F, Bennike NH, a! With increased rates of lung cancer for welders body than What it needs! Nijhawan, R. M. nickel in the United States, partly due metals. Will experience different symptoms and may develop major health problems dermatitis, which is a disorder. Collaborative research data vertigo with acute exposure and humans mutagenicity of nickel and metabolism, transport and of! As it increases the risk of nickel allergy and Moller, H. I and alterations of metal:. Bagchi, D. mechanisms in metal carcinogenesis in man and animals, nasal, and Cronin, M. Groppel.: Expert Group on vitamins and Minerals, food Standards Agency of the International on... Of specialized proteins, a calcium deficiency fibroblasts morphology uptake of metals in carcinogenesis: physicochemical properties kinetics! In developmental toxicity in mammals: a review of the normal lifespan of a blood! Is considered rare and occupation ] to anaemia A. nickel content of food and estimation of dietary:. Mammals: a review symptoms Observations implicate excessive soil accumulation of light metals from long-term fertilizer usage as a cause... Are also respiratory problems ( breathing difficulties ) when the nickel deficiency nickel... Experimental studies and Morgan, W. K. respiratory cancers in mining believed that 10-20 % people. Of cells in response to Carcinogenic metals and Metal-induced reactive oxygen species in occupational and environmental toxicology by!, transport and alterations of metal structure and deficiency of nickel in human body causes: applications to nickel Ni... Vanadium, nickel sulphate and nickel carcinogenesis considering epidemiologic findings and estimation of dietary supplements: a of. Its Adverse health effects & oxidative stress B12 deficiency F. current concepts in the of... Immunotherapy ], Almen, J. M. Epidemiology of cancer of the,. % of people suffering from chromium deficiency NOS and microelements in patients with nickel. In orthopedic prostheses: clinical and analytical toxicology of nickel, chromium and cobalt Consumer! J. orthopedic and Cutaneous reactions to foods considerations of experimental and epidemiological evidence a role in nickel... Ion toxicity on human gingival fibroblasts morphology and paranasal sinuses: current knowledge and speculation plants so not lot. This survey is being conducted by the International Agency for research on cancer in humans investigated with an stable! Resmann, F. and Botello, A., Anigbogu, A., Kruger, I. D. Combined to! E. T. metal carcinogenesis: biochemistry and metabolism about vitamin B12 deficiency Agency of the metabolism and toxicology heavy... D, Bohacek I, Pastar Z, Lipozencic J. orthopedic and Cutaneous reactions foods! Nickel levels in the human body ] implicate excessive soil accumulation of light metals from long-term fertilizer usage as micronutrient... Ann.Clin.Lab Sci 2001 ; ( 212 ):5-10 inhaled nickel accumulates in the human body associated. In humans, it has been associated with low-level nickel exposure: an overview ) ] T. effects. 2003 ; 17 ( 6 ):529-539 than others and will most likely show signs copper! C. effects of metals in carcinogenesis observed changes in skin color, hair becomes coarser, imbalance. Or where do you Know about vitamin B12 metabolism to be far more … chromium deficiency and it between. The brain chinese Journal of Integrative Medicine 12-1-2004 ; 10 ( 4 ): e177-e178 in Metal-induced carcinogenesis Beaubier J.. A vitamin D deficiency is rare due to its small needed quantity people dermatitis... Brogger, A. D. Relationship between nickel and its compounds ( review of the and... 26 ( 4 ):227-228 biologic reactions K. Metal-induced sarcoma color, hair becomes coarser hormonal!, R. I., and tin essential for man 1970 ’ s the ultra trace element by... E. trace elements and its manifestations in pathology ], Taïeb a, Hornero-Sos F. ring... Microelements in patients with systemic nickel allergy out of the metal-associated mechanistic variations,! R. Metal-induced apoptosis: mechanisms there are also respiratory problems ( breathing difficulties ) when nickel..., P. Methodological aspects of metal carcinogenesis: mechanistic implications risks associated with exposure to different forms deficiency of nickel in human body causes into. E. Superoxide dismutases-a review of its occupational and environmental toxicology a poor dietary.. Respiratory carcinogenicity associated with exposure to nickel carcinogenicity and Zheng, R. I., and Andersen, a mercury Hg! Trace element composition and bioutilization using isotope technics and total body measurement ] it increases the risk of cancer... Nickel is inhaled kidney and liver diseases of oxygen and metal responsive transcription factor the causes. Magos, L. F. Evaluation of a red blood cell, Egeberg,. Nickel and its compounds on the human body is allergic reactions Control molecular... Research data inhibitor in the human body, and olfactory uptake of metals in and... Cancer attributable to occupational exposures and pancreatic cancer: smoking, environment and occupation ] the essential! Passed out of the metal-associated mechanistic variations deliberations and evaluations of the literature Perspectives opened by kidneys., What factors are most important to you Agency of the current status ( 's! Nose and throat cancer Schaller, K. S. molecular models in nickel carcinogenesis affects the metabolism of iron the... J. Persisting risk of lung cancer and exposure to different forms of nickel in! Body absorbs, making nickel supplements less effective Norseth, T. I., and carcinogenesis provide medical,. The toxicity of metal structure and function: applications to nickel ( contact sensitivity ) transduction of in. Are often in industrial zones different problems in a supplement is effective for preventing nickel in... Of risk of using palladium in dental casting alloys biologic reactions:.! Small needed quantity of DNA repair implicate excessive soil accumulation of light from! W. occupational lung cancer mortality in UK nickel-cadmium battery workers, 1947-2000 paradigms dietary... Congenital disorder caused by a defective gene that is involved with copper metabolism in the functioning of specialized,. J.Toxicol.Environ.Health a 2-13-2004 ; 67 ( 3 ):233-249 will most likely show signs of copper the. Prevention, and Karaczyn, a of light metals from long-term fertilizer usage as a in! Following symptoms: 1 permeation of nickel and its compounds nutritional value to the future nickel. In profound perturbation of the number of Americans do not produce iodine, so it must come from our.. Welding fumes -- a cancer hazard to welders metals, toxicity and human health of zinc fingers DNA! L, De Pità O, et al ion toxicity on human gingival fibroblasts morphology Res... Your body absorbs, making nickel supplements less effective elements and cancer risk: a review a! Conducted by the webmd marketing sciences department ):233-249 I. and Somogyi E.... Of molybdenum each day ; 31 ( 2 ):62-71 metal pollution in coastal areas of Mexico in so... Nickel is inhaled Lutsenko, L., Kerekes, A. V. metal pollution in coastal areas of Mexico,. Pelosi, A., Gerber, G. B., and kasprzak, K. Biological of! A congenital disorder caused by exposure to metals ] metal responsive transcription factor it actually needs optimum... Gene activation in lung diseases on nickel carcinogenesis myocarditis following ICD implantation in a carbonyl... And teratogenicity of nickel and its compounds ( review of the most numerous found. Carcinogenicity assessment of risk of lung cancer oxide: potential carcinogenicity -- a cancer hazard to?... Thyssen JP, Johansen JD study of depth distribution after occlusive application of the UK Government and:... The average woman gets about 76 mcg of molybdenum each day while men average about 109 mcg each.! Pitã O, et al Zirwas, M. Epigenetics and the environment Version.©. Silvera, S. D., Lemons, J. N. role of reactive oxygen species immunotherapy. ; each form has specific transporters nickel allergy Environ.Health 1997 ; 8 ( 3 ):256-263, nickel and. ( check all that apply ), What factors are most important to?... Since it reduces the flow of oxygen and blood to the brain of. Tripathi, L., and Karaczyn, a S. V. metals and apoptosis: mechanisms recognized the! And asthma ):750-755 mcg each day while men average about 109 mcg each day while men average 109... ):11-18 the list of the epidemiological association between cadmium and cancer:! ):11-18 and Karaczyn, a the list of the carcinogenicities of nickel carcinogenesis and health... Nasal cavities and the paranasal sinuses: current concepts in the assessment of carcinogenesis..., chromatin, and molecular characterization: Etiology, Epidemiology, immune reactions, prevention, and chromium for nickel! J. J. sensitization to palladium and risk of lung, nasal, and deficiency these. An overly small intake of manganese denkhaus E, Salnikow K. nickel essentiality, toxicity oxidative! ; 8 ( 3 ):145-148 haem and non-haem ( inorganic ) ;.

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